An overview on synthesis and biological activity of pyrimidines

Pyrimidines represent an important class of heterocycles containing two nitrogen atoms at position 1 and 3 the six membered ring show wide range biological activities. Numerous methods for synthesis pyrimidine their diverse reactions offer enormous scope in field medicinal chemistry. Pyrimidine possesses spectrum activities including antitubercular, antibacterial, antifungal, antiviral, anti-inflammatory, antimalarial, anticancer, anti-HIV activity. The present review attempts to give brief information about various pyrimidines derivatives.